1934 - The William Cullen Library was opened in March,1934 and is located on the East Campus of Wits University and is one of the oldest buildings on campus. Its existence is due to a fire that occurred at the end of 1931 in Central Block, which was the first building at Wits University.

2010 - The old bindery at William Cullen Library. This is being cleared in preparation of the New Digitisation Centre.

2012 - Wits Digitisation Centre was established to offer digitisation services to the Wits community, galleries, libraries, archives and museums (GLAMs).

2018 - Wits University solidifies its vision of a digital campus through the launch of the Wits-NRF Digitisation Capacity Development Initiative. The initiative aimed at building capacity, enabling knowledge sharing and contribute to the skills development in digitisation in South Africa and in the Continent.

2022 - Wits-NRF Digitisation Capacity Development initiative resumed in November of 2022, after a short hiatus due to restrictions brought about the unforeseen occurrence of COVID-19 and its aftermath repercussions. This resumption of activities ran from the 10 - 29 November 2022.